WEEK1: Overview of Immunology
- What is the immune system?
- Players act in the immune system
- How various types of immune cells work in the immune system?
WEEK2: Innate Immunity
2-1: Innate Immunity- Pathogen Recognition by Innate Immunity
- Mechanism of innate immunity
- Interaction between innate immunity and adaptive immunity
Pattern recognition receptors
2-2: Innate Immunity - Disorder-specific M2 Macrophages
- Functions of macrophages
- Recent topics in the research for various types of M2 macrophages
2-3: Innate Immunity - Understanding and Manipulation of the NLRP3-inflammasome
- Colchicine inhibits activation of the NLRP3-inflammasome
- Autophagy limits activation of the NLRP3-inflammasome
WEEK 3: Adaptive Immunity 1 - Control of Immune Responses by Regulatory T Cells
- Identification of regulatory T (Treg) cells
- FoxP3 is a Treg specific transcription factor, and it controls IL-2 production
- Treg-targeting cancer immunotherapy
WEEK 4: Adaptive Immunity 2
4-1: Adaptive Immunity 2 - Immune Regulatory Mechanisms through B Cell Axis
Anti-inflammatory functions by B cell
- Regulatory function of plasmablasts to suppress Experimental Autoimmune Encephalomyelitis (EAE)
- Essential signaling factors in B cells for IL-10 production
4-2: Adaptive Immunity 2 - Vaccine & Immunological Memory
- What is vaccine (vaccination)?
- What is immunological memory?
- What are the issues in the research for immunological memory?
WEEK 5: Mucosal Immunology
- Barrier functions of epithelial cells
- Intestinal environmental factors
- Unique immune cells in the intestinal mucosa